We present a detailed description of a search for anomalous production of missing E_T (/E_T), jets, leptons (e, mu, tau), b-quarks, or additional photons in events containing two isolated, central (|\eta| < 1.0) photons with E_T > 12 GeV. The results are consistent with standard expectations, with the possible exception of one event that has in addition to the two photons a central electron, a high-E_T electromagnetic cluster, and large missing E_T. We set limits using two specific SUSY scenarios for production of diphoton events with missing E_T.