Several CDF Run 2 PYTHIA 6.2 tunes (with multiple parton
interactions) are presented and compared with HERWIG (without multiple
parton interactions) and with the ATLAS PYTHIA tune (with multiple parton
interactions). Predictions are made for the "underlying event" in high p(t)
jet production and in Drell-Yan lepton pair production at the Tevatron and
the LHC.